Projects

The aim of this work is to contribute to shed light on how cold-adapted proteins developed a molecular strategy to enhance their flexibility while still preserving sufficient stability to be...

Nardini’s laboratory is involved in the study of flavoproteins and other enzymes and their roles in several human pathologies. In addition, the group investigates wild-type enzymes and engineered variants for...

DNA regions. MucR and its homologs belong to the Ros/MucR family, which is widespread in α-proteobacteria. MucR represents a recent addition to the family of histone-like nucleoid structuring (H-NS) proteins....

Nuclear Factor I (NFI) proteins are involved in adenovirus DNA replication and regulate gene transcription, stem cell proliferation, and differentiation. They play key roles in development, cancer, and congenital disorders....

The sequence-specific transcription factor NF-Y binds the CCAAT box, one of the most frequently occurring regulatory elements in eukaryotic promoters. NF-Y functions as a heterotrimer composed of the NF-YA subunit...